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Metabolic Research Compound
5-Amino-1MQ (50mg)
NNMT inhibitor · small-molecule research compound · Research-grade, Australia
In stock · dispatched Australia-wide
View & buy on store →About 5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium) is a cell-permeable, small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). It is a methylated quinoline derivative — not a peptide — though it is commonly studied alongside metabolic research peptides and is handled the same way in the laboratory. NNMT catalyses the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, the precursor in the NAD+ salvage pathway.
Within the research community, NNMT inhibition is studied in pre-clinical models for its relationship to the NAD+ salvage pathway, methyl-donor homeostasis, and adipocyte energy metabolism. NNMT expression in white adipose tissue has been a particular focus of published pre-clinical work. 5-Amino-1MQ is supplied by Vital Research Labs strictly as a reference compound for in-vitro laboratory investigation.
Molecular target
- NNMT — nicotinamide N-methyltransferase, the enzyme that methylates nicotinamide to 1-methylnicotinamide using SAM as the methyl donor.
- NAD+ salvage pathway — studied in relation to nicotinamide availability and cellular NAD+ pools.
- Methyl-donor homeostasis — investigated for its relationship to S-adenosylmethionine availability.
Molecular & physical profile
| Compound | 5-Amino-1-methylquinolinium |
|---|---|
| Common name | 5-Amino-1MQ |
| Compound class | Small molecule (quinoline derivative) |
| Molecular target | NNMT (nicotinamide N-methyltransferase) |
| Category | Metabolic |
| CAS Number | 42464-96-0 |
| Form | Lyophilised powder |
| Appearance | White to off-white solid |
| Quantity | 10 mg per vial |
| Purity | N/A — Certificate of Analysis pending |
| Analytical methods | HPLC (purity), mass spectrometry (identity) |
| Solubility (research) | Reconstitutes in bacteriostatic or sterile water |
Batch-specific analytical values will be recorded on the Certificate of Analysis for this batch, which is pending.
Reconstitution & handling
5-Amino-1MQ is supplied as a lyophilised powder. For research handling it is typically reconstituted with bacteriostatic water; the exact volume depends on the concentration a given research protocol calls for. Handle under appropriate laboratory conditions.
Storage & stability
- Powder — store at -20 °C, protected from light and moisture.
- Reconstituted solution — store at 2–8 °C and use within 28 days.
- Handling — keep vials sealed until use; minimise freeze–thaw cycles.
Quality & testing
Every batch supplied by Vital Research Labs is analysed by an independent third-party laboratory, with purity confirmed by analytical testing. Testing for this batch is currently in progress; the Certificate of Analysis will be published in our CoA library once received.
Shipping within Australia
5-Amino-1MQ is dispatched from within Australia to Australian research customers, packaged discreetly and appropriately for a lyophilised research compound. Orders are processed on receipt of payment via bank transfer.
Frequently asked questions
Is 5-Amino-1MQ a peptide?
No. 5-Amino-1MQ is a small molecule - a methylated quinoline derivative - rather than a peptide. It is often stocked and studied alongside metabolic research peptides, and is supplied as a powder for reconstitution in the same way.
Is 5-Amino-1MQ available in Australia for research?
Yes. Vital Research Labs supplies research-grade 5-Amino-1MQ (50mg) to Australian research customers, dispatched domestically. It is provided strictly for in-vitro laboratory research and is not for human or veterinary use.
What does NNMT inhibition mean in research?
NNMT (nicotinamide N-methyltransferase) catalyses transfer of a methyl group from S-adenosylmethionine to nicotinamide. In pre-clinical research, inhibiting NNMT is studied for its effects on NAD+ salvage pathway activity and methyl-donor availability.
What purity is your 5-Amino-1MQ?
Testing for this batch is currently in progress. Purity is shown as N/A until the Certificate of Analysis is received, at which point it is published in our CoA library. We do not publish purity figures we cannot evidence.
How should 5-Amino-1MQ be stored?
The powder is stored at -20 degrees C, protected from light and moisture. Once reconstituted for research it is kept at 2-8 degrees C and typically used within 28 days.
Is 5-Amino-1MQ intended for human use?
No. 5-Amino-1MQ (50mg) supplied by Vital Research Labs is intended strictly for in-vitro laboratory research and development. It is not a medicine or therapeutic good and is not for human consumption, veterinary use, or clinical application.
Where can I buy 5-Amino-1MQ in Australia?
Vital Research Labs supplies 5-Amino-1MQ from Australian stock, dispatched from New South Wales. Orders placed before the daily cut-off are dispatched the same business day, Monday to Friday, with tracked delivery Australia-wide including Sydney, Melbourne, Brisbane, Perth and Adelaide.
How long does delivery take?
Orders are dispatched the same business day payment is confirmed, Monday to Friday. Weekend and public holiday orders are dispatched the next business day. Standard and express options are available, and express shipping is free on orders over $200. Every order is sent tracked.
Is packaging discreet?
Yes. All orders are packed in plain, unbranded outer packaging with no indication of the contents, and sent tracked via Australia Post or an equivalent carrier.
What payment methods do you accept?
We accept Visa, Mastercard and American Express, plus Apple Pay and Google Pay, all taken instantly at checkout. Bank transfer is also available if you prefer.